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Reversing the Clock: NAD+ Supplementation and Groundbreaking Gene Therapy to Combat Aging

1 April, 20231 April, 2023 Shannon 0 Comments

Reading Time: 4 minutes Nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) are precursors to nicotinamide adenine dinucleotide (NAD+), a coenzyme essential for energy metabolism, DNA repair, and cellular aging. Dr. David Sinclair’s research focuses on boosting NAD+ levels to promote healthy aging and potentially extend lifespan. Sinclair’s recent study demonstrated reversing aging effects in mice using gene therapy. Combining this with NAD+ supplementation could enhance the effects of gene therapy, but more research is needed to determine the effectiveness and safety in humans. Foods like dairy products, fish, lean meats, whole grains, and legumes can help support NAD+ production in the body.

Unleash Your Brain’s Power with Acetylcholine: The Secret to Better Memory and Focus

27 January, 20221 April, 2023 Simone C 0 Comments

Reading Time: 9 minutes Acetylcholine is a target for conditions such as Alzheimer’s Disease and dementia, and may have potential to improve or maintain brain function in healthy people. There is still some mystery surrounding this neurotransmitter though; read on for a summary of what we do know.

Diet Exercise Longevity Recharge

The Simple, Often Overlooked Ways to Optimal Health

13 January, 202213 January, 2022 Simone C 0 Comments

Reading Time: 10 minutes The holidays are over and a new year is upon us, which is perfect timing for some to renew their efforts to improve health. More often than not, attending to lifestyle basics can provide more substantial health benefits than specific hacks or interventions. We outline four of these simple but powerful measures that could help you or someone you know make 2022 the healthiest year yet.

Compound Analysis Diet Gut health

The Ultimate Guide to Ginger: Harness the Power of this Superfood for Optimal Wellness

16 December, 20214 February, 2023 Simone C 0 Comments

Reading Time: 5 minutes Ginger not only adds a warm, zesty kick to many dishes, but has many health-promoting properties. Note, this is not to encourage you to eat a gingerbread housing estate this Christmas. But modern science is providing support for several health claims.

Diet Exercise

Eating For Performance: The Importance of Carb Timing

2 December, 20212 December, 2021 Simone C 0 Comments

Reading Time: 9 minutes Carbohydrates are an important fuel source for the body and the brain, and the primary fuel used during endurance exercise. Besides type and total amount eaten, the timing of intake has a significant impact on the active btoo. Here we explore what happens when you do, and do not, provide your body with carbs before and after exercise.

Compound Analysis Longevity

Elevate Your Anti-Aging Game with Nicotinamide Mononucleotide: The Simple and Overlooked Secret to Youthful Health

18 November, 20214 February, 2023 Simone C 0 Comments

Reading Time: 8 minutes Nicotinamide mononucleotide has purported anti-ageing benefits, by reversing the natural drop in NAD+ levels with age. But there is less research exploring its use than there is for nicotinamide riboside supplements, for example. We give you the low-down on what is known to date.

Cardiovascular health Childhood health Compound Analysis Depression Exercise Gut health Immunity Nervous system health Pregnancy

Oxytocin: More Than A “Love Hormone”

4 November, 20214 November, 2021 Simone C 0 Comments

Reading Time: 9 minutes Oxytocin is well known for its roles in childbirth and childrearing, and for “feeling the love” in various interpersonal relationships. However, its importance extends far beyond these popular benefits. As a hormone and neurotransmitter that is produced in many tissues and widely distributed, it impacts a diverse range of physiological systems. Research continues to emerge which shows that it is may influence mental health, cardiovascular health, weight, pain and cancer, among others. We explore just what we know about this compound, and how you can optimise your levels.

Cardiovascular health Diet Gut health

Can Your Microbiome Cut Cholesterol?

21 October, 202121 October, 2021 Simone C 0 Comments

Reading Time: 7 minutes Healthy cholesterol levels are among the potential benefits of a healthy gut microbiome. Seeing as cholesterol has a significant impact on cardiovascular disease, which is the primary cause of death worldwide, it’s worthwhile considering the value of probiotics and prebiotics as a therapeutic tool.

Brain function Childhood health Compound Analysis Diet Longevity Nervous system health

Choline: The Nutrient You Mightn’t Have Known You Need

7 October, 20217 October, 2021 Simone C 0 Comments

Reading Time: 8 minutes Though previously underappreciated, the health world is becoming more and more aware of just how crucial choline is in many stages of life- from fetal development to advancing age. Here’s what we know about this essential nutrient with diverse roles.

Cancer Cardiovascular health Compound Analysis Diet Gut health Natural therapies

Jiaogulan: A Potential Chinese Medicine Superstar?

23 September, 202123 September, 2021 Simone C 0 Comments

Reading Time: 10 minutes Jiaogulan is a popular Chinese medicine that is traditionally used for various complaints, such as hepatitis, diabetes and cardiovascular disease. Looking at it through the lens of western science, we see it may have potential in these and more, but much more research is required to prove or disprove it.

Childhood health

The Power of Touch in Infant Development

9 September, 20219 September, 2021 Simone C 0 Comments

Reading Time: 10 minutes Touch is critical to infants’ growth and development, and possibly their survival and later health, too. We unpack the science, the special power it may hold for kids who are unwell or vulnerable, and some special considerations that could change your approach to touch.

Brain function Cardiovascular health Immunity Natural therapies Recharge

Healthy Lovin’?: The Truth About 20-second Hugs

26 August, 202126 August, 2021 Simone C 0 Comments

Reading Time: 8 minutes “20-second hugs” are purported to offer immense health benefits. There is ample evidence of the potential benefits of interpersonal touch… but the story of the 20-second hug is more nuanced.

Exercise

What Are The Physiological Limits to Our Performance?

29 July, 202129 July, 2021 Simone C 0 Comments

Reading Time: 6 minutes Extraordinary athletic performances make me wonder what is the limit to what the human body can achieve? Will elite athletes continue to perform better and break records in perpetuity? And, what degree of progress can the rest of us, non-elite, hope to attain?

Gut health

Does Your Infant’s Microbiome Impact How Fearful They Are?

1 July, 20211 July, 2021 Simone C 0 Comments

Reading Time: 6 minutes Emerging research indicates that an infant’s microbiome may be linked to their psychological wellbeing- both at the tender young age and later in life. We break down what the results of a groundbreaking pilot study into the fear response mean.

Compound Analysis

Which Supplements Boost Growth Hormone Levels?

5 May, 20215 May, 2021 Simone C 0 Comments

Reading Time: 4 minutes Human growth hormone levels can be modified in many ways, should you need to. We’ve seen that, depsite an interest

Diet

Coconut Water: King of Beverages?

23 April, 202123 April, 2021 Simone C 0 Comments

Reading Time: 8 minutes Although coconut water has been embraced in many corners as a refreshing, super-healthy drink, the evidence supporting several claims is still in its infancy. Here’s what the science actually tells us.

Compound Analysis

The Human Growth Hormone Friendly Lifestyle

15 April, 202112 August, 2021 Simone C 0 Comments

Reading Time: 8 minutes Boosting growth hormone levels doesn’t have to a pharmaceutical domain alone. Sevrall fundamantal lifestyle factors can also be otpimised…

Diet Skin health

Collagen Care: Eating Your Way to Healthy Skin

7 April, 20217 April, 2021 Simone C 0 Comments

Reading Time: 11 minutes Move over expensive cosmeceuticals and supplements- what you routinely eat can also enhance your skin’s collagen. Here we look at the evidence in favour of tweaking your intake of protein, carotenoids and antioxidants for your skin.

Exercise

Exercise with Oxygen Therapy (EWOT): Looking Beyond the Hype

1 April, 20211 April, 2021 Simone C 0 Comments

Reading Time: 10 minutes Exercise with Oxygen Therapy (EWOT) is purported to provide superior fitness gains than plain old exercise. But since good health decisions are based not just on convincing arguments, lets have a closer look at the evidence.

Cardiovascular health Immunity

The AstraZenica Vaccine and Blood Clot Controversy

26 March, 202126 March, 2021 Simone C 0 Comments

Reading Time: 6 minutes It’s understandable that some people have concern over the safety of the AstraZeneca vaccine in the wake of reports of blood clots. However, we need to peer a bit deeper to get a clear picture…

Compound Analysis Diet Natural therapies Recharge

7 Unassuming Ways You Can Combat Inflammation

18 March, 202118 March, 2021 Simone C 0 Comments

Reading Time: 3 minutes Too much inflammation over the long term accelerates the ageing process and contributes to many health conditions. Here are 7 ways of combatting this.

Recharge

6 Surprising Effects of Inflammation

9 March, 20219 March, 2021 Simone C 0 Comments

Reading Time: 3 minutes Chronic inflammation is well known to be associated with conditions such as diabetes, heart disease and arthritis. But there are also a number of less obvious ones.

Brain function Cardiovascular health Depression Longevity Recharge Respiratory health

Managing Sleep Apnoea 101

4 March, 20214 March, 2021 Simone C 0 Comments

Reading Time: 9 minutes According to sleep studies, many adults suffer from sleep apnoea. It’s far more serious than leaving you feeling sleepy- it significantly increases your risk of many lifestyle-related illnesses, car accidents- and mortality. Here is the fundamentals of what you can do about it.

Compound Analysis Recharge

Cardiolipin: A New Target for Bio-hackers

25 February, 202125 February, 2021 Simone C 0 Comments

Reading Time: 7 minutes Cardiolipin is a unique phospholipid that has particular importance to mitochondrial function, and therefore the production of energy for the entire body. Research increasingly reveals a diverse range of other roles, too, and suggests that losses are at least linked to ageing and disease. Here is a run down of what we know at this stage… and what to keep an eye out for in future, should cardiolipin prove to be a valuable target.

Compound Analysis Diet Gut health Immunity

SIBO: What You Need to Know

18 February, 202118 February, 2021 Simone C 0 Comments

Reading Time: 11 minutes The impact of Small Intestinal Bacterial Overgrowth (SIBO) is increasing steadily. Management is vital as SIBO can result in serious complications, including nutritional deficiencies and associated health conditions.

Compound Analysis

Human Growth Hormone and The Magic Zone

11 February, 202111 February, 2021 Simone C 0 Comments

Reading Time: 7 minutes Growth hormone is crucial to human growth and development, and reduces body fat, enhances protein synthesis and therefore increases muscle mass as well as strength and aerobic exercise capacity. These benefits can inspire some to seek to increase their levels. However, as we will see, increasing levels is only beneficial if you are actually deficient. Moreover, it can have some serious drawbacks for your health, and in some cases lowering levels can be preferable. Also, all methods of manipulating levels are not equal.

Diet

Can Watermelon Work Hair Wonders?

4 February, 20214 February, 2021 Simone C 0 Comments

Reading Time: 7 minutes Watermelon has numerous health benefits, purported to include increasing hair growth and combating hair loss. Let’s dive deep into the evidence for such claims.

Cardiovascular health Compound Analysis Diet Exercise Muscle health Recharge

Mitochondrial Function: Potential Ways to Maximise

28 January, 202128 January, 2021 Simone C 0 Comments

Reading Time: 6 minutes How well our mitochondria function has a significant impact on multiple facets of our health. While there is a natural tendency to decline, there are things you can do to help offset this…

Brain function Cardiovascular health Longevity Muscle health

Why Your Mitochondrial Function Matters

21 January, 202128 January, 2021 Simone C 0 Comments

Reading Time: 8 minutes Without fully functional mitochondria, your cells would have trouble using oxygen to release energy from food and regulating other processes. Here we explore factors that can compromise mitochondrial function and the significant impacts it could have on your health.

Recharge

7 Potential Botanicals to Slow Down Skin Ageing – Collagen Care

14 January, 202114 January, 2021 Simone C 0 Comments

Reading Time: 11 minutes In the hunger for collagen replenishment, numerous botanicals have been added to skincare products or recommended for consumption. These have the appeal of being natural… but just how reliable are they as safe and effective collagen boosters?

Diet Exercise Recharge

6 Ways to Capitalise on New Years’ Resolutions

7 January, 20217 January, 2021 Simone C 0 Comments

Reading Time: 5 minutes 2020, what a year that was. What can we do amongst the continued uncertainly the start of 2021 has presented us? Well, maybe it’s time for a good ol’ New Years’ Resolution. Research suggests they can be more useful than you may think. And we show you some ways of increasing your chance of success.

Compound Analysis Diet Skin health

Skin Ageing: Boosting Collagen Levels Among Women

24 December, 202013 January, 2021 Simone C 0 Comments

Reading Time: 8 minutes When oestrogen levels are low, skin collagen is lost at an increasingly dramatic rate. Phytoestrogens offer a potential way to slow down ageing.

Diet

Battle of the Oats: Steel-Cut vs Rolled

17 December, 202017 December, 2020 Simone C 0 Comments

Reading Time: 3 minutes As a minimally processed choice with a nutty taste and chewy texture, steel-cut oats have become an increasingly popular choice in the health/foodie worlds. Here we examine the evidence behind claims that they are a better nutritional choice than rolled oats.

Exercise Muscle health

EMS (Electrical Muscle Stimulation) Training: Fast Fitness or Fad?

10 December, 202010 December, 2020 Simone C 0 Comments

Reading Time: 11 minutes EMS training has been popularised in recent years becuase it helps to maximise muscular work in minimal time. Facilities providing it promise everything from increased strength, improved body composition and heart health, reduced back and joint pain, prevention of injuries, incontinence management, postnatal recovery, and cellulite reduction… Here we look for the proof.

Cardiovascular health Compound Analysis Depression Diet Exercise Gut health Immunity Recharge Skin health

‘Tis the Season to Be… Healthy?

3 December, 202014 January, 2021 Simone C 0 Comments

Reading Time: 9 minutes Each season brings along its own pleasures and health risks. Here we look at the impact the climatic changes of summer and winter bring, and what you can do to stay healthy.

Diet Exercise Longevity Muscle health

Can Omega-3 Fats Build Muscle?

26 November, 202011 February, 2021 Simone C 0 Comments

Reading Time: 8 minutes We naturally lose muscle with age, but there are ways to fight this. Besides consuming adequate protein and performing resistance training, increasing your omega-3 fatty acid intake looks to provide benefits. Here we explore how…

Exercise Muscle health

Visualisation: Can You Imagine Your Way to Fit?

19 November, 202019 November, 2020 Simone C 0 Comments

Reading Time: 7 minutes Visualisation has potential to increase the benefits of physical training programs, and may even produce some physiological adaptations when exercise is impossible. Here we outline existing evidence and recommendations.

Vitamin C, E, B3 cosmaceuticalsfor collagen

Skin health

Collagen and Skincare: Role of Vitamins C, E and B3

12 November, 202012 November, 2020 Simone C 0 Comments

Reading Time: 9 minutes Replenishing collagen is a common goal of anti-ageing skincare. Products containing vitamins C (± E) and B3 are promoted for their ability to do so… but what is the evidence?

Bone health Diet

Boning Up on Fats and Skeletal Health (Part Two): Omega-3 and Omega-6

5 November, 202012 January, 2021 Simone C 0 Comments

Reading Time: 11 minutes It’s not just calcium that matters. The quantities, ratios and source of omega-3 and omega-6 fats you get from your diet could have pronounced impact on how much inflammatory damage your bones are exposed to. Here’s what we know.

Bone health Diet

Boning Up on Fats and Skeletal Health: Part One

29 October, 202029 October, 2020 Simone C 0 Comments

Reading Time: 5 minutes Calcium and vitamin D are not the only nutrients that effect bones- fat consumption can also alter bone strength. Let’s see what impact total, saturated and unsaturated fats have…

Cardiovascular health Exercise

Heart Rate Variability Optimisation: The Underrated Index of Health

22 October, 202028 October, 2020 Simone C 2 Comments

Reading Time: 6 minutes A high Heart Rate Variability is generally a good sign for health, although it is difficult to ascertain and is regulated by a complex network of factors. Here we look at why it is so important and how it can be enhanced.

Skin health

Collagen Enhancement: Can Retinoids Defy Age?

15 October, 202017 October, 2020 Simone C 3 Comments

Reading Time: 9 minutes Retinoids have potential to tackle the loss of collagen from ageing skin. Here we examine the relative merits of different type of retinoid cosmeceuticals.

Compound Analysis Diet

Turmerosaccharides Benefits: Sweet for Joints

8 October, 202014 January, 2021 Simone C 0 Comments

Reading Time: 5 minutes Interest and research into turmerosaccharides has ramped up over the last few years. Here’s what we know about its potential as a treatment for osteoarthritis, and joint health more generally.

Diet

Nutritional Potential of Food Waste

1 October, 202015 October, 2020 Simone C 0 Comments

Reading Time: 7 minutes It’s no surprise that food waste is a problem for environmental reasons- but would you believe that on average we each throw out enough food per year to meet all of our nutritional requirements for 42 days. This included the requirements of nutrients that people are often deficient in. Here we explore the nutritional implications further and what we all can do to tap into this resource.

Cancer Cardiovascular health Depression Longevity

Telomere Maintenance for Disease Prevention?

24 September, 202026 October, 2020 Simone C 0 Comments

Reading Time: 10 minutes Telomere length can play a critical role not just in ageing, but a number of common diseases from cancer, to heart diseaase and depression. The nature of their role, and what tools we have to address it, is detailed here.

Childhood health Depression Longevity

Preserving Telomere Health: Genetic and Childhood Diseases

17 September, 202015 July, 2021 Simone C 0 Comments

Reading Time: 6 minutes While telomere shortening naturally occurs as we age, a genetic susceptibility and other dysfunctions to telomeres can have serious consequences for children. Here we look at the implications of telomere length extremes in the young.

Longevity

Telomeres: A Fail-Safe Marker of Ageing and Longevity?

10 September, 202017 June, 2021 Simone C 2 Comments

Reading Time: 7 minutes Telomeres are protective caps at the ends of DNA strands that help in keeping chromosomes stable and mutation free. Their length can and does change, with important implications on health.

Natural testosterone and strength increases

Compound Analysis Diet Exercise Muscle health

Testosterone and Muscle Building: 7 Natural Ways to Capitalise

2 September, 20202 September, 2020 Simone C 1 Comment

Reading Time: 10 minutes Healthy testosterone levels are linked with muscular physiques and strength. Here are healthy, natural ways to boost or maintain your levels.

Compound Analysis Muscle health

Testosterone and Muscle: How Much is Enough?

27 August, 20209 December, 2020 Simone C 1 Comment

Reading Time: 5 minutes It is well accepted that testosterone helps in building a muscular physique and strength. Let’s look at the evidence for and mechamisms behind this relationship, and the situations in which boosting levels may be desirable.

← Previous

Reversing the Clock: NAD+ Supplementation and Groundbreaking Gene Therapy to Combat Aging
1 April, 2023
Nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) are precursors to nicotinamide adenine dinucleotide (NAD+), a coenzyme essential for energy metabolism, DNA repair, and cellular aging. Dr. David Sinclair's research focuses on boosting NAD+ levels to promote healthy aging and potentially extend lifespan. Sinclair's recent study demonstrated reversing aging effects in mice using gene therapy. Combining this with NAD+ supplementation could enhance the effects of gene therapy, but more research is needed to determine the effectiveness and safety in humans. Foods like dairy products, fish, lean meats, whole grains, and legumes can help support NAD+ production in the body. …
Unleash Your Brain’s Power with Acetylcholine: The Secret to Better Memory and Focus
27 January, 2022
Acetylcholine is a target for conditions such as Alzheimer's Disease and dementia, and may have potential to improve or maintain brain function in healthy people. There is still some mystery surrounding this neurotransmitter though; read on for a summary of what we do know. …
The Simple, Often Overlooked Ways to Optimal Health
13 January, 2022
The holidays are over and a new year is upon us, which is perfect timing for some to renew their efforts to improve health. More often than not, attending to lifestyle basics can provide more substantial health benefits than specific hacks or interventions. We outline four of these simple but powerful measures that could help you or someone you know make 2022 the healthiest year yet. …
The Ultimate Guide to Ginger: Harness the Power of this Superfood for Optimal Wellness
16 December, 2021
Ginger not only adds a warm, zesty kick to many dishes, but has many health-promoting properties. Note, this is not to encourage you to eat a gingerbread housing estate this Christmas. But modern science is providing support for several health claims. …
Eating For Performance: The Importance of Carb Timing
2 December, 2021
Carbohydrates are an important fuel source for the body and the brain, and the primary fuel used during endurance exercise. Besides type and total amount eaten, the timing of intake has a significant impact on the active btoo. Here we explore what happens when you do, and do not, provide your body with carbs before and after exercise. …